Nowadays, anticancer therapies have to be characterized by high specificity complemented by decreased side effects. In order to achieve this goal, novel delivery systems based on nanoparticles, liposomes and micelles need to be compiled.
Our scientist worked out simple and low-cost method of producing highly stable, monodispersed and small-sized micelles, loaded with photoactive substances, suitable for anticancer therapies. Our system reveals phototoxicity, but it is non-toxic under physiological conditions. The anticancer agent is activated at wavelength range between 600-1000 nm (phototherapeutic window), so at the range where the light is able to reach deep tissues.
The micelles have high monodispersity and small size (20 nm). Additionally, they are highly stable, which is necessary for the injection into the bloodstream. The specificity of the micelle therapy is determined by low general toxicity and high phototoxicity. Moreover, the method of micelle synthesis is simple, inexpensive and effective.
- Cancer therapy
- Universal drug vehicles
Posted by Wrocławskie Centrum Badań EIT+, Posted on 19.05.2016